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Depression & Anxiety

Discover the signs that may show you’re facing anxiety or depression—and that you should ask for help. Know that you’re not alone and help is available.

I couldn’t tell if I was just down, or if it was something much more serious. Thankfully, I got help.

Anxiety is more than temporary worry. It’s a mental and physical response to the fear of something. It includes tension, worried thoughts, and physical changes (such as increased blood pressure). Symptoms can interfere with daily activities, such as work, school, and relationships. 


Studies show around 37% of people living with lupus face anxiety.

Depression is serious and causes feelings of sadness and/or a loss of interest in activities you once enjoyed—affecting how you feel, think, and act. Symptoms can be mild to severe and include: 

  • Feeling sad
  • Loss of interest
  • Weight loss or gain unrelated to dieting
  • Loss of energy
  • Increase in purposeless physical activity (such as hand-wringing or pacing)
  • Trouble sleeping or sleeping too much
  • Slowed movements and speech
  • Feeling worthless or guilty
  • Difficulty thinking, concentrating, or making decisions
  • Thoughts of death or suicide

Talk with your doctor right away if you are feeling any of these symptoms.


Around half of people with lupus deal with major depressive disorder.

If you’ve felt down or very anxious for 2 weeks in a row, or the feelings are getting in the way of living your life, find help as soon as possible. This could be from a psychiatrist, psychologist, or social worker. If you need a referral to a professional who may be able to help, ask your primary care doctor, your rheumatologist, or a local lupus organization.

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Talk to someone now.

To speak with a counselor from the National Suicide Prevention Lifeline, call them at 1-800-273-8255. The Lifeline provides free, confidential support, 24/7 to anyone who needs it. Learn more at their website.


In addition to therapy, regular exercise (with your doctor’s approval), quality sleep on a regular basis, a healthy diet, and avoiding alcohol can all help reduce symptoms of depression.

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Learn more about these symptoms.

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Joint Pain

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Skin Rashes

Icon: Lupus Hair Loss

Hair Loss

Icon: Lupus Mouth Sores

Mouth Sores

Icon: Lupus Brain Fog

Brain Fog

Icon: Kidney Issues

Kidney Issues

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& Anxiety

Icon: Lupus Muscle Pain and Weakness

Muscle Pain
& Weakness

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Heart Issues

Icon: Lupus Weight Changes